歷年研究計劃

Fundings

2024

開發新穎針對ESKAPE致病菌的抗菌藥物與機制研究 (1/3) 

Development and Mechanism Study of Novel  Antibacterial Agents against EFKAPE pathogens (I) 


2023

開發可與脂肪酸協同殺死俱多重抗藥性金黃色葡萄球菌之新穎小分子抗菌劑與機制研究(3/3) 

Development and Mechanism Study of Novel Small-Molecule Antibacterial Agents Synergistic with Fatty Acid to Kill Multidrug-Resistant S. aureus( III ) 


2022

開發可與脂肪酸協同殺死俱多重抗藥性金黃色葡萄球菌之新穎小分子抗菌劑與機制研究(2/3) 

Development and Mechanism Study of Novel Small-Molecule Antibacterial Agents Synergistic with Fatty Acid to Kill Multidrug-Resistant S. aureus( II ) 


2021

開發可與脂肪酸協同殺死俱多重抗藥性金黃色葡萄球菌之新穎小分子抗菌劑與機制研究(1/3) 

Development and Mechanism Study of Novel Small-Molecule Antibacterial Agents Synergistic with Fatty Acid to Kill Multidrug-Resistant S. aureus( I ) 

高靈敏度拉曼快篩技術於臨床重要致病菌檢測之數據庫建置與應用(2/3)

The Construction and Application of the High-Sensitive Raman Spectral Database for Rapid Identification of Clinical Important Pathogens( II )


2020

透過激活單磷酸腺苷活化蛋白質激酶去誘發異體吞噬的抗胞內細菌新藥開發與機制研究  

Development of New AMPK Activator to Induce Xenophobic Eradication against Intracellular Bacteria

高靈敏度拉曼快篩技術於臨床重要致病菌檢測之數據庫建置與應用(1/3)

The Construction and Application of the High-Sensitive Raman Spectral Database for Rapid Identification of Clinical Important Pathogens( I )


2019

從抗精神病藥吩噻嗪衍生的新穎抗菌藥物開發與機制研究

From Antipsychotic to Antibacterial: Development of Novel Antibacterial Agents from Phenothiazines


2018

國立臺灣大學-國際產學聯盟計畫II(萌芽計畫)

從先導化合物到候選藥物: 一個以多重抗藥性金黃色葡萄球菌細胞膜為標的之小分子抗菌藥物的結構優化 

From lead to candidate: structure optimization of a novel membrane-active small-molecule antibacterial agent against multiple-drug resistant Staphylococcus aureus

從抗精神病藥吩噻嗪衍生的新穎抗菌藥物開發與機制研究

From Antipsychotic to Antibacterial: Development of Novel Antibacterial Agents from Phenothiazines 

國際產學聯盟計畫-國立臺灣大學國際產學聯盟與創新資源整合計畫I(萌芽計畫 

From lead to candidate: structure optimization of a novel membrane-active small-molecule antibacterial agent against multiple-drug resistant Staphylococcus aureus


2017

從抗精神病藥吩噻嗪衍生的新穎抗菌藥物開發與機制研究

From Antipsychotic to Antibacterial: Development of Novel Antibacterial Agents from Phenothiazines 


2016

以蛋白轉位酵素為標地的抗金黃色葡萄球菌之小分子藥物研發

Development of New Small Molecule Drugs against Staphylococcus aureus by Targeting to an Essential Protein Translocase

從先導化合物到候選藥物: 一個以多重抗藥性金黃色葡萄球菌細胞膜為標的之小分子抗菌藥物的結構優化

From Lead to Candidate: Structure Optimization of a Novel Membrane-Active Small-Molecule Antibacterial Agent against Multiple-Drug Resistant Staphylococcus aureus

以宿主為標的之抗藥性沙門氏菌及土倫西斯菌感染的療法

Host Targeted Therapy for Drug Resistant Salmonella and Francisella Infection 


2015

以蛋白轉位酵素為標地的抗金黃色葡萄球菌之小分子藥物研發

Development of New Small Molecule Drugs against Staphylococcus aureus by Targeting to an Essential Protein Translocase 


2014

以蛋白轉位酵素為標地的抗金黃色葡萄球菌之小分子藥物研發

Development of New Small Molecule Drugs against Staphylococcus aureus by Targeting to an Essential Protein Translocase 

以宿主為標地之抗胞內細菌感染的新藥開發與機制研究

Development of Novel Host Cell Directed, Antibacterial Agents against Intracellular Bacteria 

發展抗多重抗藥性之金黃色葡萄球菌的新穎小分子藥物

Development of Novel Small-molecule Agents Against Multi-Drug Resistant Staphylococcus aureus


2013

出血性大腸桿菌感染的新穎治療對策-以功能失去之策略探討類志賀毒素造成細胞死亡的機制

Novel Therapeutic Strategy for the EHEC Infection 

以宿主為標地之抗胞內細菌感染的新藥開發與機制研究

Development of Novel Host Cell Directed, Antibacterial Agents Against Intracellular Bacteria 

2012

以宿主為標地之抗胞內細菌感染的新藥開發與機制研究

Development of Novel Host Cell Directed, Antibacterial Agents Against Intracellular Bacteria 

2011

針對具多重抗藥性之金黃色葡萄球菌的小分子藥物開發

Development of Small-Molecule Agents against Multi-Drug Resistant Staphylococcus aureus

2010

以誘發宿主細胞產生自體吞噬為標的之小分子抗胞內細菌藥物的開發

Development of Small-Molecule Agents against Intracellular Pathogenic Bacteria through Induction of Autophagy in Host Cell
Chiu Lab | 邱浩傑教授 實驗室
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